. Author manuscript; available in PMC: 2011 Oct 1.

Published in final edited form as: Mol Genet Metab. 2010 Jul 23;101(2-3):115–122. doi: 10.1016/j.ymgme.2010.06.020

Table 3.

Activity of alpha-l-iduronidase in spinal meninges

	IT + IV Adult (n=3)	IT + IV Early (n=4)	0.58 mg/kg IV Early (n=4)	1.57 mg/kg IV Early (n=3)
Cervical	5390 ± 2200	1330 ± 265	0.545 ± 0.242	1.32 ± 0.510
Thoracic	1060 ± 645	931 ± 1050	0.956 ± 0.268	2.49 ± 0.630
Lumbar	165 ± 75.6	1070 ± 892	1.43 ± 0.168	3.09 ± 1.03
Mean (3-regions)	2200 ± 785	1110 ± 724	0.977 ± 0.213	2.30 ± 0.585

Spinal meningeal iduronidase activity in MPS I unaffected carrier dogs was 2.43 ± 0.894, without substantial regional variation.