Table 4.

TP53 mutations in populations exposed to radon

Population	Exposure (mean WLM)	Number of cases	No cases (%) with TP53 mutations	Codon 249 AGG-ATG	Reference
Uranium miners:
New Mexico	111	19	7 mutations in 5 cases (26%)	0	Vahakangas et al. (128)
Colorado	1382	52		16 (31%)	Taylor et al. (125)
Colorado	1270	23	NS	0	McDonald et al. (129)
Germany	1011	50	NS	0	Bartsch et al. (130); Hollstein et al. (131)
Germany	NK	29	NS	2 (7%)	Yang et al. (132)
Environmental exposure:
England	9.2	17	NS	0	Lo et al. (133)
Sweden	0.25 0.5 2	139 90 14	29 (20.9%) 23 (25.6%) 6 (42.9%)	0 0 0	Yngveson et al. (151)
Missouri, USA Women	NK	Non-smokers120 Ex-smokers 11	22 (18%) 6 (54%)	0 0	Vahakangas et al. (43)

WLM, working level months (1WLM corresponds to 170 hours in a place where air contains 130 000 MeV of α-radiation in 1 liter of air; 1Bq/m³ is equivalent to 0.005 WLM)

NK, not known, NS, not studied