FIG. 1.
The MOMP vaccine protects in a vaginal model of genital infection. Female naïve, infection-immune, MOMP-vaccinated, and ovalbumin-vaccinated C57BL/6 mice were challenged intravaginally with 100 ID50 of C. muridarum. (A) Course of infection, represented as log10 chlamydial IFU recovered from cervicovaginal swabs ± standard errors of the means. (B) Percentage of culture-positive mice per group at each culture time point. (C) Percentage of mice with unilateral or bilateral hydrosalpinx at 70 days postinfection. The data represent duplicate determinations for groups of at least 5 mice each.