Table 3.
Mean hematology and clinical chemistry values of rats blood samples fed with Mentha piperita essential oil
| Parameters | Control | Mean value (test) | % change | P value |
|---|---|---|---|---|
| Initial body weight (g) | 142.50±2.9 | 159±3.61 | 111.58 | 0.001 |
| Final body weight (g) | 157.50±5 | 198.33±18.93 | 125.93 | 0.008 |
| Weight gain (%) | 110.53±2 | 124.95±14.73 | 114.42 | 0.106 |
| Erythrocyte count (RBC) (×106/IL) | 7.23±1.25 | 7.90±0.59 | 109.39 | 0.430 |
| Total white blood cell (WBC) and differential | 9400+668 | 5800±608 | 61.7 | 0.0008 |
| leukocyte count (×103/μl) | ||||
| Hemoglobin concentration (HGB) (g/dl) | 12.78±1.4 | 13.53±0.51 | 105.94 | 0.434 |
| Hematocrit (HCT) (%) | 39.63±1.7 | 38.5±0.60 | 97.16 | 0.338 |
| Platelet count (PLT) (×103/μl) | 238500±1658 | 510666.67±5401.34 | 214.12 | 0.0002 |
| Red cell distribution width [RDW (%)] | 14.75±2.14 | 13.97±1.29 | 94.69 | 0.602 |
| Mean platelet volume (MPV) | 7.600.56 | 7.07±0.45 | 92.98 | 0.236 |
| Mean corpuscular volume (MCV) (fL) | 52.93±3.84 | 50.6±4 | 95.61 | 0.471 |
| Mean corpuscular hemoglobin (MCH) (pg) | 17.78±1.37 | 17.33±0.71 | 97.52 | 0.638 |
| Mean corpuscular hemoglobin concentration | 33.75±1.95 | 35.47±0.81 | 105.09 | 0.217 |
| [MCHC (g/dl)] | ||||
| Fasting glucose (GLUC) (mg/dl) | 221±7.79 | 218.33±15.18 | 98.79 | 0.77 |
| Blood urea nitrogen (BUN) (mg/dl) | 60±5.96 | 55.23±5.25 | 92.06 | 0.322 |
| Blood creatinine (CREA) (mg/dl) | 0.64±0.1 | 0.63±0.10 | 99.21 | 0.95 |
| Uric acid | 8.18±2.45 | 4.29±0.85 | 52.44 | 0.049 |
| Total cholesterol(CHOL) (mg/dl) | 75.75±1 | 91±1 | 120.13 | 0.0000 |
| Triglycerides (TRIG) (mg/dl) | 45±9.2 | 73±8.19 | 162.22 | 0.009 |
| HDL | 45.50±4 | 67.30±0.72 | 147.91 | 0.0003 |
| LDL | 15.05±1.9 | 10.20±1.71 | 67.77 | 0.018 |
| Cholesterol/HDL ratio | 1.68±0.16 | 1.35±0.03 | 80.71 | 0.021 |
| LDL/HDL ratio | 0.33±0.03 | 0.15±0.03 | 45.93 | 0.0003 |
| SGOT | 530.75±68 | 520.67±69.41 | 98.10 | 0.855 |
| SGPT | 236.75±9 | 146.33±16.5 | 61.81 | 0.031 |
| Alkaline phosphatase (ALKP) (U/L) | 136.75±3 | 244.67±84.79 | 178.92 | 0.063 |