Table 1.
Phosphoinositide synthesis during blood-stage development of P. falciparuma
Phosphoinositide | Radioactivity (cpm)b at the following stage: |
||
---|---|---|---|
Ring | Trophozoite | Schizont | |
PI3P | 11,649 | 146,391 | 184,723 |
PI4P | 286,958 | 827,290 | 1,336,574 |
PI(3,4)P2 | ND | 12,823 | 16,750 |
PI(4,5)P2 | 1,076,872 | 2,523,291 | 2,646,058 |
Highly synchronized cultures at 10% parasitemia were used.
Values correspond to counts per minute detected after HPLC analysis in one experiment of two. ND, not detected.