Table 1.
Biofilm dispersion in mixed C. albicans SC5314 and GFP-labeled tet-NRG1 biofilmsa
| Time point (h) | % dispersed cells |
|||
|---|---|---|---|---|
| With DOX |
After switch to no DOX |
|||
| Fluorescent (GFP-tet-NRG1) | Nonfluorescent (SC5314) | Fluorescent (GFP-tet-NRG1) | Nonfluorescent (SC5314) | |
| 5 | 45.75 | 54.25 | 70.80 | 29.20 |
| 8 | 29.80 | 70.20 | 77.50 | 22.50 |
| 12 | 27 | 73 | 80.20 | 19.80 |
a
The numbers of dispersed cells from each strain were quantified using fluorescence microscopy at different time points during formation of mixed (50/50) biofilms under conditions of flow in the presence of DOX and after a subsequent switch to medium without the antibiotic.