TABLE 2.
Comparison between gene expression levels in ECOM4LA and WT MG1655 cells grown aerobically and anaerobically
| Gene name | Locus tag | Gene product | Mean fold change in expression (adjusted P value)a |
|||
|---|---|---|---|---|---|---|
| E4 +O2/WT +O2 | E4 −O2/WT −O2 | WT −O2/WT +O2 | E4 +O2/E4 −O2 | |||
| pgi | b4025 | Phosphoglucose isomerase | 3.87 (0.017) | NC | NC | NC |
| pfkABb | b3916 | 6-Phosphofructose kinase | 2.04 (0.003) | NC | 2.29 (0) | NC |
| fbaA | b2925 | Fructose bisphosphate aldolase | 3.00 (0.01) | NC | NC | NC |
| fbaB | b2097 | Fructose bisphosphate aldolase | 8.77 (0) | 3.30 (0) | 3.23 (0) | NC |
| tpiA | b3919 | Triose phosphate isomerase | 3.33 (0.005) | NC | NC | NC |
| gapA | b1779 | Glyceraldehyde 3-phosphate | 4.53 (0.02) | NC | 2.53 (0.05) | NC |
| pgk | b2926 | Phosphoglycerate kinase | 2.10 (0.02) | NC | NC | NC |
| eno | b2779 | Enolase | 3.31 (0.008) | NC | NC | NC |
| ldhA | b1380 | d-Lactate dehydrogenase | 3.36 (0.005) | NC | NC | NC |
| yieF | b3713 | NADH:menaquinone oxydoreductase | 2.47 (0.014) | 2.09 (0.001) | NC | 1.60 (0.023) |
| wrbA | b1004 | NADH:menaquinone oxydoreductase | 9.10 (0.002) | 3.22 (0.001) | 5.07 (0.003) | NC |
| frdABCDb | b4151-b4154 | Fumarate reductase | 3.60 (0.02) | NC | 4.03 (0.002) | 1.90 (0.02) |
| sdhABCDb | b0721-b0724 | Succinase dehydrogenase | −25.35 (0) | NC | −33.50 (0) | NC |
| nuoA-nuoNb | b2288-b2276 | NADH:ubiquinone oxidoreductase | −2.10 (0.005) | NC | −2.30 (0.001) | NC |
a
Benjamini-Hochberg false-discovery rate-adjusted P value. Cells were grown in triplicate. Changes of <2-fold were considered no change (NC). E4, ECOM4LA strain; WT, wild-type MG1655.
b
Average expression values are presented for large operons.