FIG. 5.

Both histone modification binding modules are required for Crb2 activity in the absence of Thr215 phosphorylation. (A and B) Phenotyping and IR survival curves were performed with strains harboring the indicated mutations as described for Fig. 2B and C. IR data are averaged from results of three independent experiments with a standard error of 10% or less. (C) Crb2 protein levels in mutant strains. Strains with the top-labeled mutations were processed for Western blotting as described for Fig. 2D.