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p27 induction following VHL loss is not prevented under hypoxia, but p21 expression is attenuated. (A and D) Western analyses of wild-type or VHL-null MEFs grown at 21, 10, 5, or 2% O2. MG, MG132. (B and C) Western analyses of serum-starved and stimulated wild-type or VHL-null MEFs in 21 or 5% O2. To allow direct comparison, membranes were transferred in the same apparatus and developed on the same pieces of film.
