FIG. 10.

The partial cellular proteomes associated with rescue of the short-term EREB2-5 growth defect by EBNA2 and Rta are distinct. EREB2-5 cells were electroporated with the indicated plasmids and cultured in the absence of β-estradiol (EBNA2 and Rta) or were transfected with empty vector and cultured in the presence of β-estradiol (+ β-e'diol). Equal amounts of protein extracts from each condition were analyzed by using a RayBio human apoptosis antibody array kit (RayBiotech). The figure shows the fold changes and standard deviations (sd) determined by comparison to results from vector-transfected EREB2-5 cells that were cultured in the absence of β-estradiol (data not shown). Fold changes greater than or equal to 1.5 are indicated by boxes, and fold changes less than or equal to −1.5 are indicated by gray shading.