FIG. 3.

The APC dissociates with similar kinetics during ΔUL97 virus infection and wild-type virus infection. HFFs infected with ΔUL97 virus (Δ) or AD169 (V) at an MOI of 3 or mock-infected (M) were harvested at the times indicated. The APC was immunoprecipitated using an anti-APC3 antibody, and coimmunoprecipitated proteins were analyzed by Western blot assay with antibodies to APC3, APC7, APC8, APC1, and Cdh1. GAPDH is shown as a negative and loading control. Lane numbers are shown below. Pre, input lysate; IP, APC3 IP; PIP, post-IP.