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MEC endocytose HIV-1 virions from infected PBMCs. Transmission electron microscopy images showing HIV-1 virions inside MEC endocytic compartments, with panels from left to right exhibiting progressive enlargement of the boxed area. The image shows HIV-1HC4 virions. Experiments were performed in duplicate with both CCR5-tropic HIV-1BaL and CXCR4-tropic HIV-1HC4. Similar experiments were repeated with MEC from two additional subjects. L, lymphocyte.
