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. 2010 Aug 11;84(20):10533–10542. doi: 10.1128/JVI.01263-10

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FIG. 4. — MEC maintain close physical contact with CD4⁺ T lymphocytes. (A) Transmission electron microscopy image showing junctions and clefts between MEC and lymphocytes (L). (B) Enlarged image of boxed area, showing junctions between cells (black arrows). Junctions between MEC and lymphocytes were observed in all samples from two individual subjects, with conditions tested in duplicate, irrespective of HIV-1 infection of lymphocytes. (C and D) Images of separate observations of lymphocyte engulfment by MEC from two individual subjects. Lymphocyte endocytosis was not dependent on HIV-1 infection of lymphocytes.