FIG. 3.

HIV Gag-specific IFN-γ T cell responses detected in the blood and genital tracts of HIV-infected HAART⁻ (A) or HAART⁺ (B) women. The responses of CD8 (filled stacked bars) and CD4 (open stacked bars) T cells in blood (top) and at the cervix (bottom) to Gag were measured in HAART⁻ (A) and HAART⁺ (B) women. Each bar represents an individual woman's response at the cervix or in blood. Background-corrected net frequencies of IFN-γ⁺ CD8 T cells are shown. The Mann-Whitney U test was used to compare unmatched samples, while the Wilcoxon rank test was used to compare matched samples. P values of ≤0.05 were considered significant. P values for CD8 and CD4 T cell comparisons are shown separately in panels A and B.