Table 1.
Fracture Risk in Gastrointestinal Disease
| Gastrointestinal disease | Low bone density* | Fracture risk |
|---|---|---|
| Celiac disease10-19 | 40% increased risk vs controls | 1.4 × normal |
| Postgastrectomy20 | 32–42% | 55% |
| Crohn's disease19,21-31 | Osteopenia: 22–55% Osteoporosis: 3–6% |
40–60% vs controls 1.3–14 × that in ulcerative colitis Greatest risk: the elderly with inflammatory bowel disease |
| Ulcerative colitis19,25-31 | Osteopenia: 32–67% Osteoporosis: 4–50% |
Risk for men slightly higher than that for women Overall, same as Crohn's disease vs no increase |
| Orthotopic liver transplant/ primary biliary cirrhosis32-34 | 46% (17% in the first year) | 36.7% |
*
Femoral neck and L-S spine.