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. 2010 Jul 8;299(3):G623–G631. doi: 10.1152/ajpgi.00242.2010

Fig. 7.

Fig. 7.

Correlation between total BA levels and ileal damage scores in rat (NEC and NEC + SC-435) and mouse (ASBT WT NEC, ASBT KO NEC, BSEP WT NEC, and BSEP OE NEC) models of NEC. Ileal luminal BA levels in rat (A) and mouse (B) models and intraenterocyte levels in rat (C) and mouse (D) models were compared with histological ileal damage scores. Rat luminal BAs (r = 0.320, P ≤ 0.05) and rat and mouse intraenterocyte BAs (r = 0.579 and 0.726, respectively; P ≤ 0.0001) are positively correlated with progression of ileal damage. Statistical analyses were performed using Spearman's rank correlation.