Table 3.

RSN 11 characteristics and statistics.

Region	Brodmann area	Center coordinates (MNI space; LPI)			PFWE		Plocal FDRq < 0.01	Plocal FDRq < 0.01
		x	y	z	HC	MDD	HC > MDD	MDD > HC
POSITIVE
Left inferior temporal gyrus	37	−48	−62	−12	<0.001	<0.001	ns	ns
Right inferior temporal gyrus	37	54	−60	−8	<0.001	<0.001	ns	ns
Left lateral occipital cortex	19	−40	−80	18	<0.001	<0.001	ns	ns
Right lateral occipital cortex	19	44	−72	14	<0.001	<0.001	ns	ns
Left supramarginal gyrus	40	−56	−28	24	<0.001	<0.001	ns	ns
	40	−46	−38	40	<0.001	<0.001	ns	ns
Right supramarginal gyrus	40	58	−40	24	<0.001	<0.001	ns	ns
	40	40	−38	40	<0.001	<0.001	ns	ns
Left posterior cingulate cortex	31	−10	−38	40	<0.001	<0.001	ns	ns
Right posterior cingulate cortex	31	12	−38	42	<0.001	<0.001	ns	ns
Left middle frontal gyrus	46	−46	36	12	0.025	ns	ns	ns
Right middle frontal gyrus	46	50	40	8	0.028	ns	ns	ns
Right precentral gyrus	6	48	8	26	0.035	ns	ns	ns
Left/right anterior cingulate gyrus	24	2	2	32	0.037	ns	ns	ns
NEGATIVE
Left hippocampus		−28	−24	−16	0.002	ns	ns	ns
Left middle temporal gyrus	21	−58	−30	−10	0.002	0.002	ns	ns
Right middle temporal gyrus	21	58	−20	−10	0.003	ns	ns	ns
Left frontal pole	10	−24	56	−4	<0.001	ns	ns	<0.001
Right frontal pole	10	32	56	−2	<0.001	<0.001	ns	ns
Left paracingulate gyrus	32	−8	32	36	0.003	ns	ns	ns
Right paracingulate gyrus	32	4	32	38	0.003	0.003	ns	ns
Left middle frontal gyrus	8	−36	16	38	ns	<0.001	ns	ns
Left/right cuneus	19	2	−78	36	<0.001	<0.001	ns	ns

Note: Group main effects are FWE-corrected for multiple comparisons, between-group contrasts are corrected for multiple comparisons using a local false discovery rate (FDR) of 1%. HC, healthy controls; MDD, major depressive disorder; ns, not significant.