Table 2.
Empirical power estimates for one-sided 0.05 level test of equal survival (H0:F1(t) = F2(t)) against shorter/longer survival of group 1 versus group 2 (H1: F1(t) > F2(t)/H1:F1(t) < F2(t)), Fj(t) ∼ exp(λj), j = 1, 2, (λ1, λ2) = (0.08, 0.04)/(0.04, 0.08), c1 and c2 refer to the percentages of censored observations
| n1 | n2 | γ1 | γ2 | c1† (%) | c2† (%) | Log-rank† | Perm† | Heinze† | IPT | IPT* | IPZ | IPZ* |
| 6 | 6 | 0.00 | 0.00 | 10/28 | 27/10 | 0.280/0.277 | 0.254/0.252 | 0.248/0.247 | 0.256/0.257 | 0.257/0.256 | 0.242/0.252 | 0.254/0.252 |
| 6 | 6 | 0.04 | 0.04 | 37/55 | 54/35 | 0.213/0.210 | 0.197/0.196 | 0.198/0.198 | 0.221/0.203 | 0.176/0.181 | 0.192/0.185 | 0.163/0.185 |
| 30 | 30 | 0.00 | 0.00 | 10/27 | 27/10 | 0.772/0.773 | 0.762/0.765 | 0.758/0.759 | 0.786/0.766 | 0.773/0.768 | 0.758/0.772 | 0.729/0.760 |
| 30 | 30 | 0.04 | 0.04 | 36/55 | 55/36 | 0.615/0.616 | 0.605/0.608 | 0.603/0.605 | 0.640/0.600 | 0.608/0.609 | 0.578/0.556 | 0.548/0.540 |
| 6 | 30 | 0.00 | 0.00 | 10/27 | 27/10 | 0.459/0.348 | 0.355/0.397 | 0.336/0.396 | 0.336/0.437 | 0.350/0.393 | 0.343/0.399 | 0.350/0.384 |
| 6 | 30 | 0.04 | 0.04 | 36/54 | 55/36 | 0.366/0.242 | 0.282/0.291 | 0.278/0.292 | 0.270/0.312 | 0.261/0.280 | 0.264/0.286 | 0.258/0.279 |
| 3 | 120 | 0.00 | 0.00 | 10/28 | 28/10 | 0.407/0.221 | 0.223/0.309 | 0.222/0.306 | 0.215/0.312 | 0.223/0.307 | 0.211/0.317 | 0.230/0.286 |
| 3 | 120 | 0.04 | 0.04 | 37/54 | 55/36 | 0.342/0.137 | 0.196/0.223 | 0.193/0.204 | 0.180/0.231 | 0.190/0.191 | 0.159/0.227 | 0.190/0.237 |
| 6 | 6 | 0.00 | 0.04 | 10/27 | 54/36 | —‡ | — | 0.223/0.211 | 0.241/0.208 | 0.210/0.211 | 0.221/0.196 | 0.196/0.194 |
| 30 | 30 | 0.00 | 0.04 | 10/27 | 55/36 | — | — | 0.676/0.654 | 0.697/0.659 | 0.690/0.638 | 0.653/0.619 | 0.650/0.637 |
| 6 | 30 | 0.00 | 0.04 | 10/27 | 55/36 | — | — | 0.329/0.351 | 0.340/0.392 | 0.332/0.341 | 0.339/0.348 | 0.323/0.351 |
| 6 | 30 | 0.04 | 0.00 | 37/55 | 28/10 | — | — | 0.277/0.313 | 0.261/0.319 | 0.278/0.313 | 0.271/0.280 | 0.293/0.286 |
| 3 | 120 | 0.00 | 0.04 | 10/27 | 55/36 | — | — | 0.223/0.298 | 0.225/0.311 | 0.211/0.305 | 0.236/0.296 | 0.212/0.296 |
| 3 | 120 | 0.04 | 0.00 | 36/55 | 28/10 | — | — | 0.177/0.198 | 0.183/0.223 | 0.179/0.226 | 0.186/0.229 | 0.190/0.245 |
imputed from the true underlying F, G1, and G2.
“—” indicates settings where the corresponding tests are not expected to maintain the nominal Type I error rates.
Taken from Heinze and others (2003).