Table 2.

Depression as a predictor of CHD and CBVD

Depression	CHD		CBVD
	No. of events/no. of participants	HR (95% CI)	No. of events/no. of participants	HR (95% CI)
Model 1
Not depressed (BDI ≤ 9)	138/18 720	1.00	100/18 720	1.00
Depressed (BDI ≥ 10)	65/4562	1.66 (1.24–2.24)***	29/4562	1.01 (0.67–1.53)
BDI score (continuous)	203/23 282	1.04 (1.02–1.06)***	129/23 282	1.01 (0.99–1.04)
Filled antidepressant prescriptions	19/927	2.04 (1.27–3.27)**	11/927	1.77 (0.95–3.29)
Model 2
Not depressed (BDI ≤ 9)	138/18 720	1.00	100/18 720	1.00
Depressed (BDI ≥ 10)	65/4562	1.51 (1.11–2.03)**	29/4562	0.92 (0.61–1.40)
BDI score (continuous)	203/23 282	1.04 (1.02–1.06)***	129/23 282	1.01 (0.98–1.04)
Filled antidepressant prescriptions	19/927	1.86 (1.15–2.99)**	11/927	1.61 (0.86–3.00)
Model 3
Not depressed (BDI ≤ 9)	138/18 720	1.00	100/18 720	1.00
Depressed (BDI ≥ 10)	65/4562	1.62 (1.20–2.18)***	29/4562	0.93 (0.60–1.42)
BDI score (continuous)	203/23 282	1.04 (1.02–1.06)***	129/23 282	0.98 (0.96–1.01)
Filled antidepressant prescriptions	19/927	1.89 (1.18–3.05)**	11/927	1.61 (0.86–3.00)
Model 4
Not depressed (BDI ≤ 9)	138/18 720	1.00	100/18 720	1.00
Depressed (BDI ≥ 10)	65/4562	1.47 (1.08–1.99)**	29/4562	0.87 (0.57–1.32)
BDI score (continuous)	203/23 282	1.03 (1.02–1.05)***	129/23 282	0.98 (0.95–1.00)
Filled antidepressant prescriptions	19/927	1.72 (1.06–2.77)*	11/927	1.52 (0.81–2.84)

*P < 0.05; **P < 0.01; ***P < 0.001.

Model 1: HR adjusted for sex, age and education.

Model 2: Model 1 additionally adjusted for alcohol consumption, sedentary lifestyle and smoking.

Model 3: Model 1 additionally adjusted for obesity, hypertension or diabetes and incident CHD or incident CBVD.

Model 4: HR adjusted for all aforementioned variables.