Table III.
Haplotype results stratified by self-reported race
| Dataset | Gene | Haplotype | Haplotype frequency (%) | OR (95% CI)a | P-value (t-statistic)a |
| AA | CASP8b | GC | 94.1 | Reference | — |
| CT | 5.3 | 0.91 (0.65–1.27) | 0.58 | ||
| FGFR2c | GCAC | 35.4 | Reference | — | |
| ATGT | 15.8 | 1.11 (0.88–1.39) | 0.38 | ||
| GTGT | 23.1 | 1.27 (1.04–1.56) | 2.05E-02 | ||
| GTAC | 7.4 | 1.08 (0.78–1.49) | 0.66 | ||
| GTAT | 8.9 | 1.25 (0.93–1.67) | 0.14 | ||
| ATAC | 3.2 | 1.11 (0.68–1.80) | 0.68 | ||
| GCAT | 2.2 | 0.77 (0.43–1.38) | 0.38 | ||
| GCGT | 2.4 | 1.10 (0.65–1.89) | 0.72 | ||
| TNRC9d | AC | 39.5 | Reference | — | |
| AT | 12.0 | 1.01 (0.77–1.31) | 0.96 | ||
| GC | 7.9 | 0.83 (0.61–1.13) | 0.24 | ||
| GT | 40.4 | 0.91 (0.77–1.07) | 0.25 | ||
| White | CASP8b | GC | 86.9 | Reference | — |
| CT | 13.1 | 0.90 (0.76–1.07) | 0.24 | ||
| FGFR2c | GCAC | 55.7 | Reference | — | |
| ATGT | 39.4 | 1.30 (1.15–1.46) | 1.91E-05 | ||
| ATAC | 2.0 | 1.32 (0.87–2.01) | 0.19 | ||
| ATGC | 1.1 | 1.00 (0.57–1.75) | 1.00 | ||
| TNRC9d | AC | 49.6 | Reference | — | |
| AT | 1.2 | 0.66 (0.35–1.22) | 0.18 | ||
| GC | 20.7 | 1.01 (0.87–1.18) | 0.87 | ||
| GT | 28.5 | 1.25 (1.09–1.42) | 1.37E-03 |
a
Adjusted for age, European ancestry and offset term.
b
CASP8 SNPs are rs1045485 and rs17468277 in relative nucleotide location order.
c
FGFR2 SNPs are rs11200014, rs2981579, rs1219648 and rs2420946 in relative nucleotide location order.
d
TNRC9 SNPs are rs12443621 and rs3803662 in relative nucleotide location order.