Table 1.
Baseline demographics by treatment, WISH trial
| Variable | Placebo (n = 175) | Soy (n = 175) | P* |
|---|---|---|---|
| Age (n) | |||
| 40 – 54 | 32 (18%) | 35 (20%) | 0.95 |
| 55 – 59 | 47 (27%) | 41 (23%) | |
| 60 – 64 | 44 (25%) | 44 (25%) | |
| 65 – 69 | 32 (18%) | 35 (20%) | |
| ≥ 70 | 20 (12%) | 20 (12%) | |
| Age (y) | 60.9 ± 6.8 | 61.0 ± 7.4 | 0.93 |
| Race (n) | |||
| White (non-Hispanic) | 118 (67%) | 105 (60%) | 0.60 |
| Black (non-Hispanic) | 9 (5%) | 12 (7%) | |
| Hispanic | 24 (14%) | 31 (18%) | |
| Asian | 19 (11%) | 19 (11%) | |
| Other | 5 (3%) | 8 (5%) | |
| Education (n) | |||
| ≤ High school | 5 (3%) | 14 (8%) | 0.03 |
| > High school | 170 (97%) | 161 (92%) | |
| Smoking history (n) | |||
| Current | 5 (3%) | 3 (2%) | 0.51 |
| Former | 63 (36%) | 72 (41%) | |
| Never smoked | 107 (61%) | 100 (57%) | |
| Years smoked | |||
| among current or former smokers (n) | 16.7 ± 12.2 | 16.9 ± 11.9 | 0.85 |
| Weight (lbs) | 153 ± 32 | 152 ± 30 | 0.82 |
| Body mass index (kg/m2) | 26.7 ± 5.4 | 26.5 ± 5.0 | 0.76 |
| Pulse rate (b/min) | 66 ± 7 | 66 ± 7 | 0.38 |
| Systolic blood pressure (mm Hg) | 119 ± 14 | 117 ± 14 | 0.45 |
| Diastolic blood pressure (mm Hg) | 75 ± 9 | 75 ± 9 | 0.55 |
| Cholesterol (mg/dL) | 222 ± 31 | 219 ± 29 | 0.31 |
| Triglycerides (mg/dL) | 109 ± 56 | 112 ± 64 | 0.89 |
| HDL-cholesterol (mg/dL) | 63 ± 17 | 62 ± 16 | 0.57 |
| LDL-cholesterol (mg/dL) | 137 ± 30 | 134 ± 26 | 0.32 |
Mean ± SD, or n (%)
*
t-test was used for all comparisons, except for years smoked, triglycerides and plasma isoflavone, where Wilcoxon rank sum test was used.