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. 2010 Jan 11;20(9):2213–2223. doi: 10.1093/cercor/bhp303

Figure 5.

Figure 5.

No significant change in mean L6 neuron position is detected 4 h after Reelin rescue. (a–e) Position of E12 BrdU+/GFP+ neurons in (a) CM-injected wild type, (b) CM-injected mutant, and (c) RM-injected mutant explants. (d) Scattergrams of cells in each treatment condition and (e) mean cell position plots ± standard error of the mean (SEM). No difference in mean position was detected in any condition. (f–j) Position of Tbr1+/GFP+ neurons in (f) CM-injected wild type, (g) CM-injected mutant, and (h) RM-injected mutant explants. (i) Cell position scattergrams and (j) mean cell position plots of Tbr1+/GFP+ neurons between conditions. A 3.2-μm difference in mean position (P = 0.09) and 12% compaction of Tbr1+/GFP+ neurons were detected (P = 0.09) in RM-rescued mutant explants compared with CM-injected mutant explants. At least 4 explants and 325 BrdU+/GFP+ cells and a minimum of 3 explants and 185 Tbr1+/GFP+ cells were compared between conditions. Error bars denote mean ± SEM in (e, j). Analysis of variance with post hoc Tukey tests were performed between treatments. Scale bar: 100 μm in (h).