Figure 6.

Pia-oriented somata and pia-directed neurites are observed coincident with preplate splitting. (a) Schematic of a coronal section of E13 wild-type cortex showing the areas of analyses. (b) Superficial Tbr1+/GFP+ cells in immature medial areas are horizontally oriented with few processes. (c) In areas of active preplate splitting, increased pia-orientation of somata is paralleled by increased numbers of pia-oriented processes. (d) In mature lateral regions, most Tbr1+/GFP+ cells are pia-oriented and show extensive dendritic outgrowth into the MZ. Scale bar: 10 μm in (b).