Table 3.
Age-Adjusted Incidence Ratesa of Heart Failure by Racial/Ethnic Group and Socioeconomic Position Across the Life Course, ARIC LC-SES Study, 1987–2004
Life Epochb | Blacks (n = 2,503) |
Whites (n = 8,519) |
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SEP Score | No. of Heart Failure Events | No. of Subjects | Total PY of Follow-up | Incidence Rate/1,000 PY | 95% CI | SEP Score | No. of Heart Failure Events | No. of Subjects | Total PY of Follow-up | Incidence Rate/1,000 PY | 95% CI | |
Overall | 221 | 2,503 | 39,554.30 | 5.23 | 4.32, 6.33 | 537 | 8,519 | 136,510 | 3.18 | 2.81, 3.60 | ||
Early lifec | ||||||||||||
Low | 3–4 | 88 | 833 | 13,123.3 | 6.09 | 4.97, 7.45 | 2–4 | 265 | 3,405 | 54,397.6 | 3.99 | 3.52, 4.53 |
Medium | 2 | 77 | 893 | 14,068.5 | 5.16 | 4.48, 5.95 | 1 | 150 | 2,551 | 40,808.7 | 3.40 | 3.08, 3.75 |
High | 0–1 | 56 | 777 | 12,362.6 | 4.38 | 3.46, 5.55 | 0 | 122 | 2,563 | 41,303.7 | 2.90 | 2.47, 4.00 |
P-trendd | 0.0540 | 0.0028 | ||||||||||
Young adulthoode | ||||||||||||
Low | 4–5 | 101 | 868 | 13,541.0 | 6.67 | 5.47, 8.13 | 3–5 | 203 | 2,211 | 35,149.8 | 4.56 | 3.96, 5.26 |
Medium | 3 | 44 | 446 | 7,037.8 | 5.27 | 4.57, 6.06 | 2 | 115 | 2,075 | 33,396.3 | 3.61 | 3.29, 3.97 |
High | 0–2 | 76 | 1,189 | 18,975.5 | 4.16 | 3.37, 5.14 | 0-1 | 219 | 4,233 | 67,963.9 | 2.86 | 2.51, 3.27 |
P-trend | 0.0018 | <0.0001 | ||||||||||
Mid-to-older adulthoodf | ||||||||||||
Low | 4–6 | 87 | 683 | 10,602.5 | 7.20 | 5.81, 8.91 | 3–6 | 265 | 2,607 | 41,347.9 | 4.73 | 4.11, 5.43 |
Medium | 3 | 79 | 791 | 12,506.5 | 5.30 | 4.60, 6.10 | 2 | 101 | 1,858 | 29,897.3 | 3.57 | 3.25, 3.92 |
High | 0–2 | 55 | 1,029 | 16,445.3 | 3.89 | 3.10, 4.89 | 0–1 | 171 | 4,054 | 65,264.8 | 2.70 | 2.34, 3.11 |
P-trend | 0.0004 | <0.0001 |
Abbreviations: ARIC, Atherosclerosis Risk in Communities; CI, confidence interval; LC-SES, Life Course Socioeconomic Status, Social Context, and Cardiovascular Disease; PY, person-years; SEP, socioeconomic position.
Incidence rates were estimated and adjusted for mean age at baseline for blacks and whites, separately.
Each categorical early life epoch measure was generated by summing the individual-level SEP factors within each life epoch and dividing the total at the 25th and 75th percentiles. “Low,” “medium,” and “high” represent the most disadvantaged to the least disadvantaged, respectively.
Summary early-life SEP was generated by summing parental educational level, occupation, and home ownership status when the participant was 10 years of age. Data on individual-level SEP indicators were self-reported during the LC-SES Study (2001).
P value from a linear trend test.
Young adulthood SEP consisted of the educational level, occupation, and home ownership status of the participant at age 30 years. Data on individual-level SEP indicators were collected during the LC-SES Study (2001).
Mid-to-older adulthood SEP was a composite of the participant's income, occupation, and home ownership status at ARIC baseline (1987–1989).