Table 3.
Mortality rates of respondents to 1999 Large Health Survey of Veterans (n= 483,091). Cox Proportional Hazard Regression Models (131,396 events).
Hazard ratio (95% CI) | ||
---|---|---|
With adjustment for psychiatric co-morbidity (and age, race, gender, education, and service- connected disability) |
With adjustment for medical co-morbidity, BMI, current smoking, exercise frequency (and age, race, gender, education, and service- connected disability) |
|
Age 40–49a | 2.70 (2.50, 2.92) | 2.13 (1.95, 2.32) |
Age 50–64 a | 5.01 (4.73, 5.49) | 3.64 (3.35, 3.96) |
Age 65–74 a | 10.76 (9.99, 11.59) | 7.30 (6.72, 7.93) |
Age 75–84 a | 19.32 (17.93, 20.81) | 12.13 (11.17, 13.18) |
Age > 84 a | 35.67 (32.98, 38.57) | 20.18 (18.49, 22.02) |
Male gender b | 1.80 (1.73, 1.87) | 1.64 (1.57, 1.71) |
Education c | 0.89 (0.88, 0.89) | 0.96 (0.95, 0.96) |
African American d | 1.06 (1.02, 1.10) | 1.00 (0.98, 1.02) |
Hispanicd | 0.78 (0.75, 0.79) | 0.81 (0.79, 0.83) |
Other race d | 1.01 (0.99, 1.04) | 0.94 (0.91, 0.96) |
Service connection less than 50% e | 1.16 (1.15, 1.18) | 1.17 (1.15, 1.18) |
Service connection greater than 50% e | 1.21 (1.19, 1.23) | 1.23 (1.21, 1.24) |
Schizophrenia f | 1.30 (1.25, 1.34) | 1.13 (1.09, 1.16) |
Bipolar disorder f | 1.06 (1.01, 1.10) | 0.99 (095, 1.04) |
Major depressive disorder f | 1.10 (1.07, 1.13) | 0.92 (0.89, 0.99) |
Other depression f | 1.23 (1.20, 1.25) | 1.00 (0.98, 1.02) |
PTSD f | 0.95 (0.93, 1.00) | 0.91 (0.86, 0.98) |
Alcohol use disorder f | 1.63 (1.59, 1.68) | 1.33 (1.29, 1.37) |
Drug use disorder f | 1.16 (1.10, 1.22) | 1.11 (1.05, 1.16) |
Medical co-morbidity g (# of conditions) |
1.08 (1.06, 1.10) | |
Physical health status (V-SF36 PCS) h | 0.97 (0.96, 0.98) | |
BMI (kg/ m2) | ||
Underweight (<18.5) i | 1.70 (1.63, 1.77) | |
Overweight (25.0–30.0)i | 1.28 (1.27, 1.31) | |
Obese (>30) i | 1.47 (1.45, 1.50) | |
Current daily smoker j | 1.20 (1.19, 1.21) | |
Exercise frequency of 3 or more times per week k |
0.89 (0.88, 0.90) |
Reference groups for covariates:
age < 40;
female gender;
High school;
Caucasian race;
no service connection;
patients without the specified psychiatric diagnosis;
patients with no co-morbid medical diagnoses;
population norm for the VSF-36 PCS subscale = 50;
normal weight (BMI 18.5–24.5);
non-smoker;
exercise frequency < 3 times per week.