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In vivo chronic alcohol exposure is associated with increased numbers of alveolar neutrophils (A) at 48h and 72h following i.t. instillation of LPS. Chronic alcohol exposure was also associated with decreased numbers of alveolar macrophages (B) at baseline, although alveolar macrophage numbers were similar at all times measured following LPS instillation. n=6-8 for each experimental group. *p<0.05 when compared to time-matched control. † p=0.07.
