Table 2. Rank order of single-nucleotide polymorphism associations chromosome 1.
Gene | SNP | Location | P-valuea | q-valueb |
---|---|---|---|---|
JAK1 | rs11208534 | Intron 3 | 4 × 10−4 | 0.1272 |
JAK1 | rs310196 | Intron 1 | 6 × 10−4 | 0.1272 |
JAK1 | rs2780831 | Intron 2 | 1 × 10−3 | 0.1413 |
JAK1 | rs310222 | Intron 7 | 0.0026 | 0.2459 |
JAK1 | rs310216 | Intron 10/exon 11 boundary | 0.0029 | 0.2459 |
IKBKE | rs1059704 | Intron | 0.0048 | 0.2591 |
JAK1 | rs2256298 | Intron 6/exon 7 boundary | 0.0055 | 0.25911 |
JAK1 | rs2991269 | Exon 15 | 0.0062 | 0.2629 |
IKBKE | rs11118132 | Intron | 0.0203 | 0.3896 |
IKBKE | rs11117909 | Intron | 0.0219 | 0.3896 |
χ2 for genotype associations.
False discovery rate significance (cutoff <0.2).