Table 1.
Nalmefene (n=166) |
Placebo (n=106) |
Statistic | P-value | |
---|---|---|---|---|
Age [mean yr (SD)] | 49.8 (9.1) | 49.3 (8.8) | F(1,270)=.22 | P=.64 |
Women (%) | 32 (19.3%) | 20 (18.9%) | χ2 =.01, df=1 | P=.93 |
Family history of alcoholism (%) |
92 (55.4%) | 63 (59.4%) | χ2 =.43, df=1 | P=.52 |
Previous alcohol treatments (#) | 1.3 (2.9) | 1.5 (3.7) | F(1,270)=.28 | P=.60 |
Number of DSM-IV alcohol dependence symptoms) |
6.6 (1.6) | 6.8 (1.4) | F(1,270)=.53 | P=.47 |
Alcohol Dependence Scale score |
17.5 (6.9) | 18.3 (7.2) | F(1,270)=.83 | P=.36 |
Heavy drinking days1per week | 3.8 (1.7) | 4.2 (1.7) | F(1,270)=3.81 | P=.052 |
Very heavy drinking days2per week |
2.0 (1.8) | 2.1 (1.7) | F(1,270)=.08 | P=.77 |
Abstinent days per week | 2.5 (1.7) | 2.1 (1.7) | F(1,270)=3.94 | P=.048 |
Beck Depression Inventory score |
13.8 (7.5) | 14.2 (8.6) | F(1,270)=.14 | P=.71 |
Beck Anxiety Inventory score | 9.2 (7.5) | 11.0 (10.0) | F(1,270)=2.78 | P=.097 |
Values are mean (SD) or number (%)
Days on which men consumed ≥5 and women consumed ≥4 standard drinks
Days on which men consumed ≥10 and women consumed ≥8 standard drinks