Table 2.
Volume of AED prescriptions, measured as DDD/1000 inhabitants day−1, stratified by drug and calendar year
| AED | 2004 DDD 1000 inhabitants day−1 | % | 2005 DDD 1000 inhabitants day−1 | % | 2006 DDD 1000 inhabitants day−1 | % | 2007 DDD 1000 inhabitants day−1 | % |
|---|---|---|---|---|---|---|---|---|
| Older AEDs | ||||||||
| Phenobarbital | 5.70 | 59.8 | 5.83 | 56.7 | 6.16 | 51.7 | 6.40 | 53.8 |
| Phenytoin | 0.01 | 0.1 | 0.03 | 0.2 | ||||
| Valproic acid | 0.52 | 5.5 | 0.66 | 6.4 | 0.66 | 5.5 | 0.78 | 6.5 |
| Carbamazepine | 0.70 | 7.4 | 0.64 | 6.2 | 0.64 | 5.3 | 0.74 | 6.2 |
| Clonazepam | 0.09 | 0.9 | 0.13 | 1.2 | 0.21 | 1.7 | 0.23 | 2.0 |
| Primidone | 0.05 | 0.6 | 0.07 | 0.7 | 0.09 | 0.8 | 0.11 | 0.9 |
| Barbexaclone | 0.09 | 0.9 | 0.07 | 0.7 | 0.05 | 0.4 | 0.05 | 0.4 |
| Valpromide | 0.02 | 0.2 | ||||||
| Total | 7.18 | 75.3 | 7.39 | 72.0 | 7.81 | 65.5 | 8.34 | 70.1 |
| Newer AEDs | ||||||||
| Levetiracetam | 0.05 | 0.6 | 0.08 | 0.8 | 0.19 | 1.6 | 0.26 | 2.1 |
| Tiagabine | 0.04 | 0.4 | ||||||
| Lamotrigine | 0.41 | 4.4 | 0.47 | 4.5 | 0.47 | 3.9 | 0.63 | 5.3 |
| Gabapentin | 1.58 | 16,6 | 1.66 | 16.2 | 1.35 | 11.3 | 0.94 | 7.9 |
| Topiramate | 0.13 | 1.4 | 0.14 | 1.3 | 0.13 | 1.1 | 0.14 | 1.2 |
| Oxcarbazepine | 0.14 | 1.4 | 0.28 | 2.8 | 0.45 | 3.8 | 0.56 | 4.7 |
| Pregabalin | 0.25 | 2.4 | 1.51 | 12.7 | 1.03 | 8.6 | ||
| Total | 2.35 | 24.7 | 2.88 | 28.0 | 4.11 | 34.5 | 3.56 | 29.9 |
| Total AEDs | 9.53 | 100 | 10.27 | 100 | 11.92 | 100 | 11.89 | 100 |