Table 2.
Mean Number of Tumors in the Proximal and Distal Colon in LID Versus Wild-Type Mice 20 wk After the Last AOM Injection
| Tumor location | Mean number of tumors (SD) in the LID mice (n = 30)a | Mean number of tumors (SD) in the wild-type mice (n = 11) | P-valueb |
|---|---|---|---|
| Proximal | 1.93 (1.53) | 7.64 (1.63) | <0.0001 |
| % of adenocarcinomas | 90 | 94 | |
| Distal | 6.03 (2.86) | 5.36 (2.50) | 0.50 |
| % of adenocarcinomas | 90 | 90 |
One LID mouse out of 30 did not develop tumors.
P-value was calculated via a Student's t-test.