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Superoxide production in TRPV4−/− and TRPV4+/+ macrophages with and without 4αPDD. A: TRPV4+/+ and TRPV4−/− macrophages stained with MitoTracker Red after treatment with 4αPDD. B: mean fluorescence intensities of MitoTracker Red in TRPV4+/+ and TRPV4−/− macrophages with and without treatment with 4αPDD. *P < 0.05 vs. baseline value in the same genotype. #P < 0.05 vs. TRPV4−/− group after same treatment.
