Figure 2.

Neuroprotection against 6-OHDA toxicity following delayed subchronic intranigral administration of 2R,4R-APDC (10 nmol in 4 μL) translates into functional recovery of motor deficits. (a) Bar graph of mean percentage forelimb use asymmetry ± s.e.m in vehicle and 2R,4R-APDC (10 nmol)-treated animals, **P < 0.01, vehicle versus 2R,4R-APDC. (b) Bar graph of amphetamine-induced rotational behavior, expressed as net ipsilateral turns over 60 minutes ± s.e.m in vehicle and 2R,4R-APDC-treated animals, ***P < .001, vehicle versus 2R,4R-APDC.