TABLE 1.

Amino acid residues in integrin αvβ3 that are involved in NRG1 binding

Amino acid residues in integrin αvβ3 within 6 Å of NRG1 in the docking model were identified using Swiss-pdb viewer.

αv	β3
Asp-84, Arg-115, Met-118, Lys-119, Gln-120	Pro-169, Pro-170, Glu-171, Ala-172, Leu-173, Tyr-178, Asp-179, Met-180, Lys-181
Gln-145, Asp-146, Ile-147, Asp-148, Ala-149, Asp-150, Gly-151, Gly-151, Gln-152
Phe-177, Tyr-178, Gln-190, Gln-182
Gln-207, Ala-209, Thr-210, Arg-211, Thr-212, Ala-213, Gln-214, Ala-215, Asp-218