FIGURE 4.

Induction of apoptosis in HEL cells by G6 and its derivatives. HEL cells were treated with 25 μm of the different drugs for 48 h and then stained with annexin V-FITC and propidium iodide followed by flow cytometric analysis. A, shown are representative flow cytometry profiles from one of four independent results. B, quantification of the number of cells in early apoptosis (i.e. annexin V-positive and propidium iodide-negative). The data shown are the means ± S.D. from four independent experiments. *, p < 0.05 with respect to DMSO; #, p < 0.05 with respect to non-stilbenoids.