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Models for the methyl transfer reactions catalyzed by the SET7/9 Y245A mutant. Models of the Y245A mutant for the first methyl transfer reaction with TAF10-K189 (A), the second methyl transfer reaction with TAF10-K189me1 (B), and the third methyl transfer reaction with TAF10-K189me2 (C). Residues and hydrogen bonds are depicted as in Fig. 3.
