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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Wiley Interdiscip Rev Syst Biol Med. 2010 Nov–Dec;2(6):708–733. doi: 10.1002/wsbm.93

TABLE 3.

Gene-Set Enrichment Tools

Tool Name URL Class Annotation Database References
Onto-express http://vortex.cs.wayne.edu/projects.htm#Onto-Express SEA GO + pathway 220
FunSpec http://funspec.med.utoronto.ca/ SEA MIPS + GO; Published datasets 221
MAPPFinder http://www.genmapp.org/ SEA GO + pathway MAPPs 222
GARBAN http://garban.tecnun.es SEA Multiple sources and KEGG 223
EASE http://david.abcc.ncifcrf.gov/ SEA Multiple sources 224
FatiGO/FatiWise/FatiGO+ http://www.fatigo.org/ SEA Multiple sources 218
gfinder http://www.bioinformatics.polimi.it/GFINDer/ SEA GO + OMIM 217
WebGestalt http://bioinfo.vanderbilt.edu/webgestalt/ SEA Multiple sources 225
FACT http://www.factweb.de/ SEA Multiple sources 226
GOCluster http://www.biozentrum.unibas.ch/gocluster/ SEA GO + protein–protein interaction 227
L2L http://depts.washington.edu/l2l/ SEA Multiple sources 228
BayGO http://blasto.iq.usp.br/~tkoide/BayGO/ SEA GO, KEGG 229
g:Profiler http://biit.cs.ut.ee/gprofiler/ SEA Multiple sources 230
IGA GSEA GO or user defined 231
GSEA http://www.broad.mit.edu/gsea/ GSEA Multiple sources 215
FuncCluster http://corneliu.henegar.info/FunCluster.htm GSEA GO + KEGG 232
FIVA http://bioinformatics.biol.rug.nl/standalone/fiva/ GSEA Multiple sources 155
Gazer http://integromics.kobic.re.kr/GAzer/index.faces GSEA Multiple sources 233
FatiScan http://www.babelomics.org/ GSEA Multiple sources 234
GeneTrail http://genetrail.bioinf.uni-sb.de/enrichment_analysis.php GSEA Multiple sources 216
PalS http://pals.bioinfo.cnio.es/ MEA Published datasets; GO +
    KEGG + Reactome pathways
235
DAVID http://david.abcc.ncifcrf.gov/ SEA Multiple sources 214
FunNet http://www.funnet.info/ Unclear GO + KEGG 236
Lists2Networks http://www.lists2networks.org SEA Multiple sources 270