APPENDIX Table II.
Metabolic hormone measurements
| Pre-treatment | End of treatment | |||
|---|---|---|---|---|
| TIB-8.5h | TIB-5.5h | TIB-8.5 | TIB-5.5h | |
| 24-h serum leptin (µg/L) | 13.1 (10.2) | 12.4 (9.5) | 9.7 (7.2) | 9.1 (9.2) |
| 24-h acylated ghrelin (ng/L) | 81 (50) | 73 (38) | 75 (40) | 84 (47)* |
| 24-h serum growth hormone (µg/L) | 0.88 (0.49) | 0.79 (0.34) | 0.81 (0.38) | 0.95 (0.47) |
| 24-h plasma epinephrine (pmol/L) | 129 (38) | 136 (58) | 140 (45) | 114 (30)** |
| 24-h plasma norepinephrine (pmol/L) | 1171 (589) | 1291 (829) | 1161 (512) | 1104 (481) |
| 24-h serum cortisol (nmol/L) | 196 (21) | 198 (25) | 190 (22) | 193 (23) |
| 24-h serum TSH (mU/L) | 1.2 (0.6) | 1.2 (0.5) | ||
| 24-h serum free T4 (pmol/L) | 16.1 (1.2) | 16.5 (1.2) | ||
| (ng/dL) | 1.25 (0.10) | 1.28 (0.10) | ||
| Serum T3 (nmol/L, n=7) | 1.89 (0.18) | 1.95 (0.24) | ||
Data are mean (SD) values (n=10 except for T3 where n=7).
*
P = 0.039,
**
P = 0.005: effect of sleep restriction at the end of the 5.5-h vs. 8.5-h time in bed condition based on a mixed linear model controlling for crossover study design (treatment period) and final body composition.
TSH: thyroid stimulating hormone; T4: thyroxine; T3: triiodothyronin