Table1. Candidate reference genes evaluated in this study.
Gene symbol | Gene product name | Accession number | Function |
---|---|---|---|
Ablim1† | Actin-binding LIM protein 1 | NM_001044394 | Mediates interaction between actin filaments and cytoplasmic targets |
Actb§ | Actin, beta | NM_031144 | Cytoskeletal structural protein |
B2m§ | Beta-2 microglobulin | NM_012512 | Beta-chain of MHC class I molecules |
Efha1† | EF-hand domain family, member A1 | NM_134396 | Stimulates tubulin polymerization; calcium ion binding |
Gapdh§ | Glyceraldehyde-3-phosphate dehydrogenase | NM_017008 | Oxidoreductase in glycolysis and gluconeogenesis |
Hprt1§ | Hypoxanthine phosphoribosyltransferase 1 | NM_012583 | Catalytic enzyme in purine salvage pathway |
Ldhal6b† | Lactate dehydrogenase A-like 6B | NM_183334 | Catalyzes lactate-pyruvate interconversion; involved in glycolysis |
Magi2† | Membrane associated guanylate kinase, WW and PDZ domain containing 2 | NM_053621 | Synaptic scaffolding molecule |
Mterf† | Mitochondrial transcription termination factor | NM_053499 | Regulates mtDNA transcription |
Sdha§ | Succinate dehydrogenase complex, subunit A | NM_130428 | Catalyzes mitochondrial succinate oxidation |
Sptbn1† | Spectrin, beta, non-erythrocytic 1 | NM_001013130 | Actin cross-linking and molecular scaffold protein |
Tbc1d22a† | TBC1 domain family, member 22A | XM_001078492 | Regulates Rab GTPase activity |
Wrnip1† | Werner helicase interacting protein 1 | NM_172332 | Interacts with Werner syndrome ATP-dependent helicase; potential role in replication and other nuclear transactions |
Ywhaz§ | Tyrosine 3-monooxygenase | NM_013011 | Component of the mitochondrial import stimulation factor; regulates signal transduction by binding to phosphorylated serine residues on a variety of signaling molecules |
Candidate identified as mid-90% fluorescent intensity in microarray screen;
Candidate identified in literature review.