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. 2010 Oct 7;5(10):e13273. doi: 10.1371/journal.pone.0013273

Figure 6. Modelfree analysis.

Figure 6

(A) Order parameters S2 of the I214V mutant of RaPrPC(121–228). Regular secondary structure elements are indicated on the top. The program Fastmodelfree [63] was used to perform the calculation. Unavailable S2 values for a few residues are due to the absence of data or failure in the data fitting. (B) Differences in S2 values between the wild-type and the mutant. The difference is calculated according to the equation: ΔS2 = S2 mutant−S2 wild-type. The absence of ΔS2 values for residues result from unavailable S2 values for either the wild-type or the mutant. (C) ΔS2 values are mapped onto the tertiary structures of the I214V mutant: blue for ΔS2≥0, red for ΔS2<0, and grey for ΔS2 unavailable. This ribbon diagram is generated by PyMol (kindly provided by Prof. DeLano WL).