Figure 1. Effects of hemorrhage on timing-based mortality.
Three groups of mice were studied: H group (hemorrhaged animals); P group (methicillin-susceptible S. aureus (MSSA)-induced pneumonia only; n = 15) and HP group (animals hemorrhaged before MSSA-induced pneumonia; n = 15). Pneumonia was induced in mice with MSSA (7×105 CFU) 2, 4, 8, 24, 48, or 96 hours after hemorrhage (HP-H2, -H4, -H8, -H24, -H48, and -H96 groups, respectively) and survival was compared with mice with P group and H group. Survival rates are expressed as percentage and are representative of three independent experiments. & P<0.05 versus all others; *P<0.05 versus P group.