Table 1. Hemorrhagic shock worsens biological consequences of methicillin-susceptible S. aureus (MSSA) pneumonia.
Sham (S) group | Hemorrhage (H) group | Pneumonia (P) group | Hemorrhage-Pneumonia (HP) group | |
Lactate (mmol/l) | 3.5±0.5 | 4.2±1.3 | 4.6±1.3& | 6.0±1.5& * |
pH | 7.34±0.03 | 7.32±0.04 | 7.26±0.03& | 7.22±0.01& * |
HCO3- (mmol/l) | 28.5±1.1 | 24.5±2.1& | 26.8±1.6 | 24.5±3.0& * |
BE (mmol/l) | +0.4±0.2 | −1.4±0.2& | −0.9±0.8 | −2.8±0.7& * |
PcO2 (kPa) | 6.4±1.1 | 5.8±1.6 | 3.4±1.2& | 3.8±1.3& |
PcCO2 (kPa) | 7.3±0.9 | 6.8±0.4 | 8.5±0.7 | 9.1±1.3 |
SvO2 (%) | 59±12 | 41±12& | 29±18& | 35±19& |
Blood glucose (mmol/l) | 1.87±0.29 | 1.88±0.45 | 0.81±0.3& | 1.36±0.23& * |
BE: Base Excess, PcO2: Central venous Pression in O2, PcCO2: Central venous Pression in CO2, SvO2: Venous saturation in oxygen. Blood samples were collected via cardiac route (right atria) 24 hours after hemorrhage (H group) or MSSA pneumonia onset (P and HP groups).
& P≤0.05 versus S group,
*P≤0.05 versus P group.