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. 2010 Oct 7;5(10):e13202. doi: 10.1371/journal.pone.0013202

Figure 2. Solution Structures of Tandem AT3-UIM12 in Free and Ub-Bound Forms.

Figure 2

A, Ensemble of 10 structures superimposed on the polypeptide backbones of the α-helix of UIM1. B, Ensemble of 10 structures superimposed on those of UIM2. The helical portions of AT3-UIM12 show relative high definition, but the linker region is unstructured and flexible. No tertiary contacts between helices are observed. C, Backbone superposition of 10 lowest-energy structures of AT3-UIM12 in the Ub-bound form. D, Ribbon representation of AT3-UIM12 structure in the Ub-bound form. The structure of the Ub-bound form includes two α-helices, helix-1 (residues 226–238) and helix-2 (residues 247–256), and a linker loop region (residues 239–244) between them. The figures were generated using MOLMOL.