Table 1.

Functional correlates of prokaryote homology for yeast genes

Data	Eubacterial	Archaebacterial	All	P value (arch ≤ bact)
Expression level: number of tags	73.81 (61.03– 86.46)	164.64 (131.0–198.5)	85.89 (78.80–93.09)	< 0.0001
Closeness centrality in interaction network	0.314 (0.312–0.316)	0.324 (0.321–0.327)	0.316 (0.315–0.317)	< 0.0001
Degree in interaction network	15.91 (15.20–16.62)	20.90 (19.33–22.48)	18.02 (17.60–18.48)	< 0.0001
Number of paralogs in yeast genome	13.13 (12.09–14.16)	8.02 (6.89–9.22)	7.58 (7.14–8.04)	1

Values are listed by domain of best BLAST hit, showing means and 95% bootstrap percentile CIs for the mean of each parameter (calculated using the nonparametric bootstrap). P values are bootstrap probabilities for the mean of the statistic in archaebacterial homologs being less than or equal to the mean in eubacterial homologs, based on 10,000 replicates.