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RNP-8 and GLD-3 work synergistically to promote oocyte development. (A) Poly(A) tail lengths of gld-1 mRNA in wild-type, rnp-8(0), gld-3(RNAi), rnp-8(0); gld-3(RNAi), and gld-2(RNAi) adults, measured by gel analysis of PCR products (Upper) and by sequencing cloned PCR isolates (mean ± SEM) (Lower). (B) Removal of RNP-8 enhances gld-3 oogenesis defects. (C) Model for combinatorial control of germ cell fate specification and development by GLD-2/GLD-3 and GLD-2/RNP-8.
