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. 2010 Sep 28;123(20):3576–3586. doi: 10.1242/jcs.070391

Fig. 1.

Fig. 1.

Plakoglobin regulates keratinocyte motility by increasing cell velocity. (A) Representative tracks of ten randomly chosen PG+/− and PG−/− cells from five 5-hour trials involving a minimum of 50 cells per trial. The intersection of the x- and y-axes was taken as the starting point of each cell path. Each tick mark on the axes represents 50 pixels. (B) Graph showing the net displacement (left) and total distance traveled (right) of PG+/− and PG−/− cells (mean ± s.d.; n≥3 trials, with at least 50 cells per trial). (C) Directed migration index (ratio of the ‘net displacement’ and ‘total distance traveled’) of PG+/− and PG−/− cells. (D) The average velocity of ≥50 PG+/− and PG−/− cells, from three independent experiments (mean ± s.d.; n≥3 trials, with at least 50 cells per trial). (E) Velocity maps of a representative PG+/− (solid line) and PG−/− (dotted line) keratinocyte. Cells were followed for 5 hours, with velocity measured at 5-minute intervals.