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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Neurobiol Aging. 2010 Jul 1;32(12):2322.e19–2322.e27. doi: 10.1016/j.neurobiolaging.2010.05.023

Table 3. Classification of MCI-C vs. MCI-NC.

Sensitivity is the proportion of MCI-C correctly classified, and specificity is the proportion of MCI-NC correctly classified, based on their baseline scores. Parentheses show the predictive value of the SPARE-AD score alone, when evaluated on the entire sample of 239 MCI patients; the rest of the numbers are from a subset of 120, for which both CSF and SPARE-AD values were available.

Sensitivity (%) Specificity (%) Classification rate (%) AUC
SPARE-AD 94.7(89.8) 37.8(37.0) 55.8(52.3) 0.734(0.660)
SPARE-AD & t-tau 84.2 51.2 61.7 0.677
SPARE-AD & Aβ42 84.2 50.0 60.8 0.671
SPARE-AD & t-tau & Aβ42 84.2 50.0 60.8 0.671
SPARE-AD & t-tau/Aβ42 84.2 50.0 60.8 0.671
SPARE-AD & p-tau 81.6 51.2 60.8 0.664
SPARE-AD & p-tau181P/Aβ42 81.6 50.0 60.0 0.658
t-tau 47.4 61.0. 56.7 0.595
LR-TAA model 84.2 29.3 46.7 0.579
t-tau/Aβ42 86.8 35.4 51.7 0.564
p-tau181p 76.3 33.0 46.7 0.551
p-tau181P/Aβ42 89.5 23.2 44.2 0.548
t-tau & Aβ42 78.9 30.5 45.8 0.547
Aβ42 89.5 24.4 45.0 0.545