Table 1.
Characteristics of group with conformational differences in region between −1,115 and −784 in the P1 promoter of the IGF-1 gene divided into variant carriers and non variant carriers according to the GC repeats estimation
| Parameters | Variant carriers | Non variant carriers | All subjects with observed conformational differences in region between −1,115 and −784 in the P1 promoter of the IGF-1 gene |
|---|---|---|---|
| Mean ± SD (N = 12) | Mean ± SD (N = 26) | Mean ± SD (N = 38) | |
| Weight (kg) | 85.8 ± 15 | 78.8 ± 14.0 | 81 ± 14.5 |
| Height (cm) | 170.1 ± 7.8 | 163.9 ± 9.4 | 165.9 ± 9.3 |
| BMI (kg/m2) | 29.8 ± 5.9 | 29.1 ± 3.8 | 29.3 ± 4.5 |
| TC (mg/dL) | 198.2 ± 53.2 | 202.2 ± 56.6 | 201 ± 54.8 |
| HDL (mg/dL) | 44.8 ± 11.2 | 52.0 ± 13.3 | 49.7 ± 13.0 |
| LDL (mg/dL) | 124.8 ± 43.8 | 122.6 ± 50.1 | 123.3 ± 47.6 |
| Lp(a) (g/L) | 0.12 ± 0.14 | 0.19 ± 0.24 | 0.17 ± 0.22 |
| Apo B-100 [g/L] | 1.02 ± 0.31 | 1.1 ± 0.32 | 1.04 ± 0.31 |
| Apo A1(g/L) | 1.46 ± 0.2 | 1.57 ± 0.23 | 1.5 ± 0.2 |
| IGF/BMI | 8.1 ± 3.6 | 6.3 ± 1.9 | 6.9 ± 2.66 |
| IGF-1 (ng/mL) | 227.6 ± 73.7 | 181.6 ± 47.9 | 196 ± 60.3 |
| IGFBP3 (ng/mL) | 2,092.6 ± 721.3 | 2,081.7 ± 504.5 | 2,085.2 ± 653.7 |
| Diabetes mellitus (%) | 13.16 | 23.68 | 36.84 |
| Smoking cigaretes (%) | 13.16 | 7.89 | 21.05 |
| Hypertension (%) | 23.68 | 50 | 73.68 |
ApoA1 apoprotein A1, ApoB100 apoprotein B-100, BMI body mass index, HDL,LDL lipoproteins, IGF insulin like growth factor, Lp(a) lipoprotein a, TC total cholesterol, IGFBP3 IGF binding protein number 3