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. 2010 Oct 7;16(37):4691–4696. doi: 10.3748/wjg.v16.i37.4691

Table 2.

Multivariate analysis of baseline characteristics between patients with and without lamivudine resistance

Adjusted P value Adjusted OR (95% CI)
Male 0.842 1.080 (0.506-2.307)
Chinese 0.343 2.099 (0.454-9.707)
Mean age, yr 0.448 0.989 (0.960-1.018)
Cirrhosis 0.977 1.011 (0.479-2.133)
Baseline bilirubin, μmol/L 0.457 0.996 (0.984-1.007)
Baseline albumin, g/L 0.108 0.950 (0.893-1.011)
Baseline ALT, U/L 0.099 0.997 (0.994-1.000)
Baseline AST, U/L 0.521 1.001 (0.998-1.005)
HBeAg positive 0.005 2.857 (1.383-5.903)
Baseline log HBV DNA, IU/mL 0.014 1.415 (1.073-1.865)
Baseline abnormal ALT 0.923 0.959 (0.405-2.27)

Baseline hepatitis B virus (HBV) DNA and hepatitis B "e" antigen (HBeAg) status were independent predictors of lamivudine resistance. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase.