Relative risks of (A) all-cause and (B) cardiovascular disease (CVD) mortality by cardiorespiratory fitness quintiles for 40,451 (2657 all-cause and 943 CVD deaths) men and 12,831 (375 all-cause and 90 CVD deaths) women aged 20–100 years without CVD or cancer in the Aerobics Center Longitudinal Study. Cardiorespiratory fitness is measured by total duration during a maximal treadmill exercise test. Relative risks (95% confidence intervals) are shown inside the bars and adjusted for age, year of examination, body mass index, smoking status, abnormal electrocardiogram, hypertension, diabetes, hypercholesterolemia, and family history of CVD.