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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Mol Microbiol. 2010 Oct;78(1):138–157. doi: 10.1111/j.1365-2958.2010.07317.x

Table 5.

In vivo fitness of siderophore biosynthesis mutants following cochallenge competition experiments with P. mirabilis HI4320.

Strain defecta Bladder Kidneys
CIb P-valuec CIb P-valuec
PbtSR 0.195 0.850 0.040 0.034
NrpSR 7.900 0.004 30.95 0.027
NrpSPbtSR 2.069 0.019 1.470 0.051
a

Strain defect noted as synthetaseS and/or receptorR mutant in the proteobactin (Pbt) and/or yersiniabactin-related (Nrp) siderophore system.

b

Competitive index, determined by dividing the ratio of the CFU of wild-type to mutant at 7 days post-infection by the ratio present in the input inoculum. Significant CI>1 indicates mutant has a fitness defect.

c

CI P-value as determined by Wilcoxon signed-rank test. Significant P-values are bolded.